产品详情
简单介绍:
Anti-FDPS antibody (120-419) (STJ28311)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-FDPS (120-419) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:100-1:500 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | FDPS |
Gene ID: | 2224 |
Uniprot ID: | FPPS_HUMAN |
Immunogen Region: | 120-419 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-419 of human FPS/FDPS (NP_001995.1). |
Immunogen Sequence: | IGGKYNRGLTVVVAFRELVE PRKQDADSLQRAWTVGWCVE LLQAFFLVADDIMDSSLTRR GQICWYQKPGVGLDAINDAN LLEACIYRLLKLYCREQPYY LNLIELFLQSSYQTEIGQTL DLLTAPQGNVDLVRFTEKRY KSIVKYKTAFYSFYLPIAAA MYMAGIDGEKEHANAKKILL EMGEFFQIQDDYLDLFGDPS VTGKIGTDIQDNKCSWLVVQ CLQRATPEQYQILKENYGQ |
Function | Key enzyme in isoprenoid biosesynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate. |
Protein Name | Farnesyl Pyrophosphate Synthase Fpp Synthase Fps (2e -6e-Farnesyl Diphosphate Synthase Dimethylallyltranstransferase Farnesyl Diphosphate Synthase Geranyltranstransferase |
Database Links | Reactome: R-HSA-191273 Reactome: R-HSA-2426168 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Farnesyl Pyrophosphate Synthase antibody Anti-Fpp Synthase antibody Anti-Fps antibody Anti-(2e -6e-Farnesyl Diphosphate Synthase antibody Anti-Dimethylallyltranstransferase antibody Anti-Farnesyl Diphosphate Synthase antibody Anti-Geranyltranstransferase antibody Anti-FDPS antibody Anti-FPS antibody Anti-KIAA1293 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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