产品详情

  • 产品名称：Anti-DOCK4 antibody (150-450) (STJ118209)

  • 产品型号：STJ118209
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-DOCK4 antibody (150-450) (STJ118209)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DOCK4 (150-450) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DOCK4
Gene ID: 9732
Uniprot ID: DOCK4_HUMAN
Immunogen Region: 150-450
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 150-450 of human DOCK4 (NP_055520.3).
Immunogen Sequence: LDWGNEQLGLDLVPRKEYAM VDPEDISITELYRLMEHRHR KKDTPVQASSHHLFVQMKSL MCSNLGEELEVIFSLFDSKE NRPISERFFLRLNRNGLPKA PDKPERHCSLFVDLGSSELR KDIYITVHIIRIGRMGAGEK KNACSVQYRRPFGCAVLSIA DLLTGETKDDLILKVYMCNT ESEWYQIHENIIKKLNARYN LTGSNAGLAVSLQLLHGDIE QIRREYSSVFSHGVSITRK
Tissue Specificity Widely expressed at low level. Highly expressed in skeletal muscle, prostate and ovary. Isoform 2: May be specifically expressed in the brain and eye.
Function Functions as a guanine nucleotide exchange factor (GEF) that promotes the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form. Involved in regulation of adherens junction between cells. Plays a role in cell migration. Isoform 2: Has a higher guanine nucleotide exchange factor activity compared to other isoforms.
Protein Name Dedicator Of Cytokinesis Protein 4
Database Links Reactome: R-HSA-9013149
Reactome: R-HSA-9013404
Reactome: R-HSA-9013408
Reactome: R-HSA-983231
Cellular Localisation Cell Membrane
Cell Projection
Cytoplasm
Cytosol
Colocalizes With Epha2
Rhog And Cttn/Cortactin At The Tip Of Protrusions In Migrating Cells
Alternative Antibody Names Anti-Dedicator Of Cytokinesis Protein 4 antibody
Anti-DOCK4 antibody
Anti-KIAA0716 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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