产品详情

  • 产品名称：Anti-DLST antibody (1-290) (STJ115261)

  • 产品型号：STJ115261
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-DLST antibody (1-290) (STJ115261)
详情介绍：
Host: Rabbit
Applications: WB/IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DLST (1-290) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC-P 1:50-1:100
IF/ICC 1:50-1:100
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DLST
Gene ID: 1743
Uniprot ID: ODO2_HUMAN
Immunogen Region: 1-290
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human DLST (NP_001924.2).
Immunogen Sequence: MLSRSRCVSRAFSRSLSAFQ KGNCPLGRRSLPGVSLCQGP GYPNSRKVVINNSVFSVRFF RTTAVCKDDLVTVKTPAFAE SVTEGDVRWEKAVGDTVAED EVVCEIETDKTSVQVPSPAN GVIEALLVPDGGKVEGGTPL FTLRKTGAAPAKAKPAEAPA AAAPKAEPTAAAVPPPAAPI PTQMPPVPSPSQPPSGKPVS AVKPTVAPPLAEPGAGKGLR SEHREKMNRMRQRIAQRLK
Function Dihydrolipoamide succinyltransferase (E2) component of the 2-oxoglutarate dehydrogenase complex. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A.
Protein Name Dihydrolipoyllysine-Residue Succinyltransferase Component Of 2-Oxoglutarate Dehydrogenase Complex - Mitochondrial
2-Oxoglutarate Dehydrogenase Complex Component E2
Ogdc-E2
Dihydrolipoamide Succinyltransferase Component Of 2-Oxoglutarate Dehydrogenase Complex
E2k
Database Links Reactome: R-HSA-389661
Reactome: R-HSA-71064
Reactome: R-HSA-71403
Cellular Localisation Mitochondrion Matrix
Nucleus
Mainly Localizes In The Mitochondrion
A Small Fraction Localizes To The Nucleus
Where The 2-Oxoglutarate Dehydrogenase Complex Is Required For Histone Succinylation
Alternative Antibody Names Anti-Dihydrolipoyllysine-Residue Succinyltransferase Component Of 2-Oxoglutarate Dehydrogenase Complex - Mitochondrial antibody
Anti-2-Oxoglutarate Dehydrogenase Complex Component E2 antibody
Anti-Ogdc-E2 antibody
Anti-Dihydrolipoamide Succinyltransferase Component Of 2-Oxoglutarate Dehydrogenase Complex antibody
Anti-E2k antibody
Anti-DLST antibody
Anti-DLTS antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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