产品详情
简单介绍:
Anti-CD34 antibody (150-250 aa) [PT0038] (STJ196875)
详情介绍:
Host: | Mouse |
Applications: | IHC/IF |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Mouse monoclonal antibody anti-Hematopoietic progenitor cell antigen CD34 (150-250 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
Clonality: | Monoclonal |
Clone ID: | PT0038 |
Conjugation: | Unconjugated |
Isotype: | IgG1k |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Dilution Range: | IHC-P 1:100-500 IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CD34 |
Gene ID: | 947 |
Uniprot ID: | CD34_HUMAN |
Immunogen Region: | 150-250 aa |
Specificity: | This antibody detects endogenous levels of human CD34. Heat-induced epitope retrievals (HIER) TRIS-EDTA of pH8.0 was highly recommended as antigen repair method in paraffin section |
Immunogen: | Synthesized peptide derived from the human CD34 at the amino acid range 150-250 |
Post Translational Modifications | Highly glycosylated. Phosphorylated on serine residues by PKC. |
Function | Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. |
Protein Name | Hematopoietic Progenitor Cell Antigen Cd34 Cd Antigen Cd34 |
Database Links | Reactome: R-HSA-198933 P28906-1 |
Cellular Localisation | Membrane Single-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Hematopoietic Progenitor Cell Antigen Cd34 antibody Anti-Cd Antigen Cd34 antibody Anti-CD34 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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