产品详情

  • 产品名称：Anti-DEFA3 antibody (20-94) (STJ27293)

  • 产品型号：STJ27293
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-DEFA3 antibody (20-94) (STJ27293)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DEFA3 (20-94) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DEFA3
Gene ID: 1668
Uniprot ID: DEF3_HUMAN
Immunogen Region: 20-94
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-94 of human DEFA3 (NP_005208.1).
Immunogen Sequence: EPLQARADEVAAAPEQIAAD IPEVVVSLAWDESLAPKHPG SRKNMDCYCRIPACIAGERR YGTCIYQGRLWAFCC
Function Effector molecule of the innate immune system that acts via antibiotic-like properties against a broad array of infectious agents including bacteria, fungi, and viruses. Possesses the ability to neutralize bacterial toxins such as B. anthracis lethal factor, Clostridium difficile cytotoxin B as well as leukocidin produced by Staphylococcus aureus. Blocks also herpes simplex virus infection by interacting with envelope glycoprotein B and thus preventing its binding to heparan sulfate, the receptor for attachment.
Protein Name Neutrophil Defensin 3
Defensin - Alpha 3
Hnp-3
Hp-3
Hp3 Cleaved Into - Hp 3-56 - Neutrophil Defensin 2
Hnp-2
Hp-2
Hp2
Database Links Reactome: R-HSA-1461973
Reactome: R-HSA-1462054
Cellular Localisation Secreted
Alternative Antibody Names Anti-Neutrophil Defensin 3 antibody
Anti-Defensin - Alpha 3 antibody
Anti-Hnp-3 antibody
Anti-Hp-3 antibody
Anti-Hp3 Cleaved Into - Hp 3-56 - Neutrophil Defensin 2 antibody
Anti-Hnp-2 antibody
Anti-Hp-2 antibody
Anti-Hp2 antibody
Anti-DEFA3 antibody
Anti-DEF3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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