产品详情

  • 产品名称：Mouse EFNB2 (Ephrin B2) Sandwich ELISA Kit (STJE0008588)

  • 产品型号：STJE0008588
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Mouse EFNB2 (Ephrin B2) Sandwich ELISA Kit (STJE0008588)
详情介绍：
Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.054ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This EFNB2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Efnb2
Gene ID: 13642
Uniprot ID: EFNB2_MOUSE
Sample Type: serum, plasma, tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Expressed in inner and outer pillar cells of the organ of Corti (at protein level). Expressed on lateral floor plate cells, specifically on commissural axon segments that have passed through the floor plate. Expressed in cells of the retinal ganglion cell layer during retinal axon guidance to the optic disk. Expressed in myogenic progenitor cells.
Post Translational Modifications Inducible phosphorylation of tyrosine residues in the cytoplasmic domain.
Function Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.
Protein Name Ephrin-B2
Elf-2
Eph-Related Receptor Tyrosine Kinase Ligand 5
Lerk-5
Htk Ligand
Htk-L
Database Links Reactome: R-MMU-2682334
Reactome: -MMU-3928662
Reactome: -MMU-3928664
Reactome: -MMU-3928665
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Adherens Junction
Alternative ELISA Names Ephrin-B2 ELISA kit
Elf-2 ELISA kit
Eph-Related Receptor Tyrosine Kinase Ligand 5 ELISA kit
Lerk-5 ELISA kit
Htk Ligand ELISA kit
Htk-L ELISA kit
Efnb2 ELISA kit
Elf2 ELISA kit
Epl5 ELISA kit
Eplg5 ELISA kit
Htkl ELISA kit
Lerk5 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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