产品详情
简单介绍:
Mouse TRPM7 (Transient Receptor Potential Cation Channel Subfamily M, Member 7) Sandwich ELISA Kit (STJE0012823)
详情介绍:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 34pg/mL |
Detection Limit: | 78.1-5000pg/mL |
Short Description: | This TRPM7 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | Trpm7 |
Gene ID: | 58800 |
Uniprot ID: | TRPM7_MOUSE |
Sample Type: | tissue homogenates or other biological fluids. |
Tissue Specificity | Found to be expressed in brain and skeletal muscle, with stronger signals in kidney, heart, liver and spleen. |
Post Translational Modifications | Autophosphorylated. |
Function | Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1). |
Protein Name | Transient Receptor Potential Cation Channel Subfamily M Member 7 Channel-Kinase 1 Long Transient Receptor Potential Channel 7 Ltrpc-7 Ltrpc7 Transient Receptor Potential-Phospholipase C-Interacting Kinase Trp-Plik |
Database Links | Reactome: R-MMU-3295583 |
Cellular Localisation | Membrane Multi-Pass Membrane Protein |
Alternative ELISA Names | Transient Receptor Potential Cation Channel Subfamily M Member 7 ELISA kit Channel-Kinase 1 ELISA kit Long Transient Receptor Potential Channel 7 ELISA kit Ltrpc-7 ELISA kit Ltrpc7 ELISA kit Transient Receptor Potential-Phospholipase C-Interacting Kinase ELISA kit Trp-Plik ELISA kit Trpm7 ELISA kit Chak ELISA kit Ltrpc7 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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