产品详情

  • 产品名称：Mouse TP63 (Tumor Protein P63) Sandwich ELISA Kit (STJE0012746)

  • 产品型号：STJE0012746
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Mouse TP63 (Tumor Protein P63) Sandwich ELISA Kit (STJE0012746)
详情介绍：
Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.054ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This TP63 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Tp63
Gene ID: 22061
Uniprot ID: P63_MOUSE
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Widely expressed, notably in thymus, prostate, placenta and skeletal muscle, although the precise isoform varies according to tissue type. Progenitor cell layers of skin, breast and prostate express high levels of DeltaN-type isoforms.
Post Translational Modifications May be sumoylated. Ubiquitinated. Polyubiquitination involves WWP1 and leads to proteasomal degradation of this protein.
Function Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Activates transcription of the p21 promoter. Activates RIPK4 transcription. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge.
Protein Name Tumor Protein 63
P63
Transformation-Related Protein 63
Tp63
Tumor Protein P73-Like
P73l
Database Links Reactome: R-MMU-6804759
Cellular Localisation Nucleus
Alternative ELISA Names Tumor Protein 63 ELISA kit
P63 ELISA kit
Transformation-Related Protein 63 ELISA kit
Tp63 ELISA kit
Tumor Protein P73-Like ELISA kit
P73l ELISA kit
Tp63 ELISA kit
P63 ELISA kit
P73l ELISA kit
Tp73l ELISA kit
Trp63 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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