产品详情

  • 产品名称：Mouse PTHrP (Parathyroid Hormone Related Protein) Sandwich ELISA Kit Ready-To-Use (STJE0018137)

  • 产品型号：STJE0018137
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Mouse PTHrP (Parathyroid Hormone Related Protein) Sandwich ELISA Kit Ready-To-Use (STJE0018137)
详情介绍：
Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 5.6pg/mL
Detection Limit: 15.6-1000pg/mL
Short Description: This PTHrP Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: PthlhUniprot ID=PTHR_MOUSE"
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity
Post Translational Modifications There are several secretory forms, including osteostatin, arising from endoproteolytic cleavage of the initial translation product. Each of these secretory forms is believed to have one or more of its own receptors that mediates the normal paracrine, autocrine and endocrine actions.
Function Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Up-regulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath. Osteostatin is a potent inhibitor of osteoclastic bone resorption.
Protein Name Parathyroid Hormone-Related Protein
Pth-Rp
Pthrp
Parathyroid Hormone-Like Protein
Plp Cleaved Into - Osteostatin
Database Links
Cellular Localisation Cytoplasm
Nucleus
Secreted
Alternative ELISA Names Parathyroid Hormone-Related Protein ELISA kit
Pth-Rp ELISA kit
Pthrp ELISA kit
Parathyroid Hormone-Like Protein ELISA kit
Plp Cleaved Into - Osteostatin ELISA kit
Pthlh ELISA kit
Pthrp ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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