产品详情

  • 产品名称：Anti-DUOX1 antibody (1312-1551) (STJ111316)

  • 产品型号：STJ111316
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-DUOX1 antibody (1312-1551) (STJ111316)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DUOX1 (1312-1551) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DUOX1
Gene ID: 53905
Uniprot ID: DUOX1_HUMAN
Immunogen Region: 1312-1551
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1312-1551 of human DUOX1 (NP_059130.2).
Immunogen Sequence: ALGTTEYHPFTLTSAPHEDT LSLHIRAAGPWTTRLREIYS APTGDRCARYPKLYLDGPFG EGHQEWHKFEVSVLVGGGIG VTPFASILKDLVFKSSVSCQ VFCKKIYFIWVTRTQRQFEW LADIIREVEENDHQDLVSVH IYITQLAEKFDLRTTMLYIC ERHFQKVLNRSLFTGLRSIT HFGRPPFEPFFNSLQEVHPQ VRKIGVFSCGPPGMTKNVEK ACQLINRQDRTHFSHHYEN
Tissue Specificity Expressed in thyrocytes and tracheal surface epithelial cells (at protein level). Expressed in thyroid, trachea, bronchium, and to a lower extent, in placenta, testis, prostate, pancreas and heart.
Post Translational Modifications N-glycosylated.
Function Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
Protein Name Dual Oxidase 1
Large Nox 1
Long Nox 1
Nadph Thyroid Oxidase 1
Thyroid Oxidase 1
Database Links Reactome: R-HSA-209968
Cellular Localisation Apical Cell Membrane
Multi-Pass Membrane Protein
Localizes To The Apical Membrane Of Epithelial Cells
Alternative Antibody Names Anti-Dual Oxidase 1 antibody
Anti-Large Nox 1 antibody
Anti-Long Nox 1 antibody
Anti-Nadph Thyroid Oxidase 1 antibody
Anti-Thyroid Oxidase 1 antibody
Anti-DUOX1 antibody
Anti-DUOX antibody
Anti-LNOX1 antibody
Anti-THOX1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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