产品详情
简单介绍:
Anti-DPYD antibody (1-173) (STJ23425)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-DPYD (1-173) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | DPYD |
Gene ID: | 1806 |
Uniprot ID: | DPYD_HUMAN |
Immunogen Region: | 1-173 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human DPYD (NP_000101.2). |
Immunogen Sequence: | MAPVLSKDSADIESILALNP RTQTHATLCSTSAKKLDKKH WKRNPDKNCFNCEKLENNFD DIKHTTLGERGALREAMRCL KCADAPCQKSCPTNLDIKSF ITSIANKNYYGAAKMIFSDN PLGLTCGMVCPTSDLCVGGC NLYATEEGPINIGGLQQFAT ETLILAFSLMNHL |
Tissue Specificity | Found in most tissues with greatest activity found in liver and peripheral blood mononuclear cells. |
Function | Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil. |
Protein Name | Dihydropyrimidine Dehydrogenase Nadp(+ Dhpdhase Dpd Dihydrothymine Dehydrogenase Dihydrouracil Dehydrogenase |
Database Links | Reactome: R-HSA-73621 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Dihydropyrimidine Dehydrogenase Nadp(+ antibody Anti-Dhpdhase antibody Anti-Dpd antibody Anti-Dihydrothymine Dehydrogenase antibody Anti-Dihydrouracil Dehydrogenase antibody Anti-DPYD antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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