产品详情

  • 产品名称：Anti-DLG1 antibody (70-120 aa) (STJ192925)

  • 产品型号：STJ192925
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-DLG1 antibody (70-120 aa) (STJ192925)
详情介绍：
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Disks large homolog 1 (70-120 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DLG1
Gene ID: 1739
Uniprot ID: DLG1_HUMAN
Immunogen Region: 70-120 aa
Specificity: DLG1 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from part of the human protein at the amino acid range 70-120
Post Translational Modifications Phosphorylated by MAPK12. Phosphorylation of Ser-232 regulates association with GRIN2A. Ubiquitinated.by MARCHF2 which results in its degradation.
Function Essential multidomain scaffolding protein required for normal development. Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. Functional regulator of Kv1.5 channel. During long-term depression in hippocampal neurons, it recruits ADAM10 to the plasma membrane.
Protein Name Disks Large Homolog 1
Synapse-Associated Protein 97
Sap-97
Sap97
Hdlg
Database Links Reactome: R-HSA-399719
Reactome: R-HSA-438066
Reactome: R-HSA-442982
Reactome: R-HSA-447038
Reactome: R-HSA-451308
Reactome: R-HSA-5673001
Reactome: R-HSA-8849932
Reactome: R-HSA-9609736
Reactome: R-HSA-9617324
Reactome: R-HSA-9620244
Cellular Localisation Membrane
Peripheral Membrane Protein
Basolateral Cell Membrane
Endoplasmic Reticulum Membrane
Postsynaptic Density
Synapse
Cell Membrane
Sarcolemma
Apical Cell Membrane
Cell Junction
Cytoplasm
Colocalizes With Epb41 At Regions Of Intercellular Contacts
Basolateral In Epithelial Cells
May Also Associate With Endoplasmic Reticulum Membranes
Mainly Found In Neurons Soma
Moderately Found At Postsynaptic Densities
Alternative Antibody Names Anti-Disks Large Homolog 1 antibody
Anti-Synapse-Associated Protein 97 antibody
Anti-Sap-97 antibody
Anti-Sap97 antibody
Anti-Hdlg antibody
Anti-DLG1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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