产品详情

  • 产品名称：Anti-CD3 antibody [OKT3, RPA-T4, OKT8] {APC/FITC/PerCP-Cyanine5.5} (STJA0002510)

  • 产品型号：STJA0002510
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CD3 antibody [OKT3, RPA-T4, OKT8] {APC/FITC/PerCP-Cyanine5.5} (STJA0002510)
详情介绍：
Applications: FC
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: NA monoclonal antibody anti-CD3-APC/CD4-FITC/CD8 Alpha-PerCP-CyanIne5.5 is suitable for use in Flow Cytometry research applications.
Clonality: Monoclonal
Clone ID: OKT3, RPA-T4, OKT8
Conjugation: APC/FITC/PerCP-Cyanine5.5
Formulation: PBS with 0.05% Proclin300, 1% BSA
Storage Instruction: Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.
Background This product is a FC antibody cocktail made up of APC Anti-Human CD3 Antibody [Clone: OKT3] (Mouse IgG2a, k) , FITC Anti-Human CD4 Antibody [Clone: RPA-T4] (Mouse IgG1, k) and PE/Cyanine5.5 Anti-Human CD8a Antibody [Clone: OKT-8] (Mouse IgG2a, k). CD3 is a heterotetrameric protein consisting of a CD3 Gamma, a CD Delta and 2 CD3 Epsilon. It forms complex with TCR. OKT-3 recognize human CD3 Epsilon. Human CD3 is expressed on the surface of T cells and NKT cells. CD4 is also called Leu-3 or T4. It s a single-chain type I transmembrane glycoprotein, mainly expressed on the surface of T cells, and monocytes/macrophages. In T cells, CD4 forms complex with TCR/CD3 and play important roles in T cell immunity. The target of HIV is CD4+ T cells. Reduction of CD4+ T cells is the main reason of defected immunity after HIV infection. CD8 is mainly expressed on cytotoxic T cells and also some subpopulations of NK cells. CD8 forms dimer function. In most cells, CD8 is a heterodimer consisting of CD8a and CD8b, but in NK cells nearly all CD8 is homodimer of CD8a. CD8a can form co-receptor with MHC-I restricted TCR to promote T cell antigen recognition and activation.

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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