产品详情
简单介绍:
Anti-DEFB114 antibody (6-56 aa) (STJ196629)
详情介绍:
Host: | Rabbit |
Applications: | IHC/IF |
Reactivity: | Human/Rat/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Beta-defensin 114 (6-56 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | IHC-P 1:50-200 IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | DEFB114 |
Gene ID: | 245928 |
Uniprot ID: | DB114_HUMAN |
Immunogen Region: | 6-56 aa |
Specificity: | This antibody detects endogenous levels of DB114 at Human |
Immunogen: | Synthesized peptide derived from the human DB114 at the amino acid range 6-56 |
Function | Has a salt-sensitive antimicrobial activity against Gram-negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality. |
Protein Name | Beta-Defensin 114 Beta-Defensin 14 Defb-14 Defensin - Beta 114 |
Database Links | Reactome: R-HSA-1461957 Reactome: R-HSA-1461973 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Beta-Defensin 114 antibody Anti-Beta-Defensin 14 antibody Anti-Defb-14 antibody Anti-Defensin - Beta 114 antibody Anti-DEFB114 antibody Anti-DEFB14 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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