产品详情

  • 产品名称：Anti-Cytokeratin 5 antibody [EP1601Y] (STJ16100352)

  • 产品型号：STJ16100352
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-Cytokeratin 5 antibody [EP1601Y] (STJ16100352)
详情介绍：
Host: Rabbit
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Cytokeratin 5 is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: EP1601Y
Conjugation: Unconjugated
Isotype: IgG
Formulation: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% sodium="" azide<="" td="">
Dilution Range: IHC 1: 50 – 1:200
Storage Instruction: Store at 2-8°C upon receipt.
Gene Symbol: KRT5
Gene ID: 3852
Uniprot ID: K2C5_HUMAN
Tissue Specificity Expressed in corneal epithelium (at protein level). Expressed in keratinocytes (at protein level).
Post Translational Modifications Phosphorylated by CDK1, AURKB and Rho-kinase, phosphorylation is regulated by the cell cycle. Thr-24 phosphorylation, mediated by CDK1, peaks during prometaphase or metaphase cells with phosphorylated filamentous structures evident throughout the cytoplasm during early mitosis. CDK1 phosphorylates Thr-24 in mitotic cells at the site of injury. O-glycosylated.
Function Required for the formation of keratin intermediate filaments in the basal epidermis and maintenance of the skin barrier in response to mechanical stress. Regulates the recruitment of Langerhans cells to the epidermis, potentially by modulation of the abundance of macrophage chemotactic cytokines, macrophage inflammatory cytokines and CTNND1 localization in keratinocytes.
Protein Name Keratin - Type Ii Cytoskeletal 5
58 Kda Cytokeratin
Cytokeratin-5
Ck-5
Keratin-5
K5
Type-Ii Keratin Kb5
Database Links Reactome: R-HSA-446107
Reactome: R-HSA-6805567
Reactome: R-HSA-6809371
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Keratin - Type Ii Cytoskeletal 5 antibody
Anti-58 Kda Cytokeratin antibody
Anti-Cytokeratin-5 antibody
Anti-Ck-5 antibody
Anti-Keratin-5 antibody
Anti-K5 antibody
Anti-Type-Ii Keratin Kb5 antibody
Anti-KRT5 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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