产品详情
简单介绍:
Anti-Cytokeratin 19 antibody (Full length) [ZR143] (STJ180563)
详情介绍:
Host: | Rabbit |
Applications: | IHC-P |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit monoclonal antibody anti-Cytokeratin 19 (Full length) is suitable for use in Immunohistochemistry research applications. |
Clonality: | Monoclonal |
Clone ID: | ZR143 |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% proclin<="" td=""> 0.1%> |
Purification: | Affinity purified |
Dilution Range: | 1:100-200 |
Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
Gene Symbol: | KRT19 |
Gene ID: | 3880 |
Uniprot ID: | K1C19_HUMAN |
Immunogen Region: | Full length |
Specificity: | Positive Control: Breast carcinoma |
Immunogen: | Recombinant human full-length KRT19 protein |
Tissue Specificity | Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin. |
Function | Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. |
Protein Name | Keratin - Type I Cytoskeletal 19 Cytokeratin-19 Ck-19 Keratin-19 K19 |
Database Links | Reactome: R-HSA-6805567 Reactome: R-HSA-6809371 |
Alternative Antibody Names | Anti-Keratin - Type I Cytoskeletal 19 antibody Anti-Cytokeratin-19 antibody Anti-Ck-19 antibody Anti-Keratin-19 antibody Anti-K19 antibody Anti-KRT19 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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