产品详情

  • 产品名称：Mouse ChT (High Affinity Choline Transporter) Sandwich ELISA Kit Ready-To-Use (STJE0014324)

  • 产品型号：STJE0014324
  • 产品厂商：ST john's laboratory
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
Mouse ChT (High Affinity Choline Transporter) Sandwich ELISA Kit Ready-To-Use (STJE0014324)
详情介绍：
Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.055ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This ChT Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Slc5a7
Gene ID: 63993
Uniprot ID: SC5A7_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Found in spinal cord, brain-stem, mid-brain and striatum. Specific for cholinergic neurons.
Post Translational Modifications Phosphorylated by PKC and dephosphorylated by PP1/PP2A.
Function High-affinity Na(+)-coupled choline transmembrane symporter. Functions as an electrogenic, voltage-dependent transporter with variable charge/choline stoichiometry. Choline uptake and choline-induced current is also Cl(-)-dependent where Cl(-) is likely a regulatory ion rather than cotransported ion. Plays a critical role in acetylcholine (ACh) synthesis by taking up the substrate choline from the synaptic cleft into the presynaptic nerve terminals after neurotransmitter release. SLC5A7/CHT1-mediated choline high-affinity transport in cholinergic neurons is the rate-limiting step for production of ACh, thereby facilitating communication by subsequent action potentials. Localized predominantly in presynaptic terminal intracellular organelles, and translocated to the plasma membrane in active form in response to neuronal activity.
Protein Name High Affinity Choline Transporter 1
Hemicholinium-3-Sensitive Choline Transporter
Cht
Solute Carrier Family 5 Member 7
Database Links Reactome: R-MMU-264642
Reactome: -MMU-425366
Cellular Localisation Presynaptic Cell Membrane
Multi-Pass Membrane Protein
Cell Projection
Axon
Early Endosome Membrane
Cytoplasmic Vesicle
Secretory Vesicle
Synaptic Vesicle Membrane
Localized To Motor Neuron Axons
Alternative ELISA Names High Affinity Choline Transporter 1 ELISA kit
Hemicholinium-3-Sensitive Choline Transporter ELISA kit
Cht ELISA kit
Solute Carrier Family 5 Member 7 ELISA kit
Slc5a7 ELISA kit
Cht1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
姓名：
电话：
您的需求：
 
网站地图