产品详情
简单介绍:
Anti-CREB1 antibody (100-149 aa) (STJ92462)
详情介绍:
Host: | Rabbit |
Applications: | WB/IHC/IF/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Cyclic AMP-responsive element-binding protein 1 (100-149 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:40000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CREB1 |
Gene ID: | 1385 |
Uniprot ID: | CREB1_HUMAN |
Immunogen Region: | 100-149 aa |
Specificity: | CREB-1 Polyclonal Antibody detects endogenous levels of CREB-1 protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human CREB at the amino acid range 100-149 |
Function | Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-119 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. Regulates the expression of apoptotic and inflammatory response factors in cardiomyocytes in response to ERFE-mediated activation of AKT signaling. |
Protein Name | Cyclic Amp-Responsive Element-Binding Protein 1 Creb-1 Camp-Responsive Element-Binding Protein 1 |
Database Links | Reactome: R-HSA-111931 Reactome: R-HSA-111932 Reactome: R-HSA-198693 Reactome: R-HSA-199920 Reactome: R-HSA-2151201 Reactome: R-HSA-2197563 Reactome: R-HSA-375165 Reactome: R-HSA-400253 Reactome: R-HSA-442720 Reactome: R-HSA-442729 Reactome: R-HSA-442742 Reactome: R-HSA-5674400 Reactome: R-HSA-881907 Reactome: R-HSA-9022692 Reactome: R-HSA-9022699 Reactome: R-HSA-9022702 Reactome: R-HSA-9022707 Reactome: R-HSA-9031628 Reactome: R-HSA-9609690 Reactome: R-HSA-9616222 Reactome: R-HSA-9634638 Reactome: R-HSA-9660821 Reactome: R-HSA-9664323 Reactome: R-HSA-9707616 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Cyclic Amp-Responsive Element-Binding Protein 1 antibody Anti-Creb-1 antibody Anti-Camp-Responsive Element-Binding Protein 1 antibody Anti-CREB1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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