产品详情

  • 产品名称：Anti-CASTOR2 antibody (104-154 aa) (STJ196082)

  • 产品型号：STJ196082
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CASTOR2 antibody (104-154 aa) (STJ196082)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Cytosolic arginine sensor for mTORC1 subunit 2 (104-154 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunogen Region: 104-154 aa
Specificity: This antibody detects endogenous levels of GATL1 at Human
Immunogen: Synthesized peptide derived from the human GATL1 at the amino acid range 104-154
Function Functions as a negative regulator of the TORC1 signaling pathway through the GATOR complex. As part of homodimers or heterodimers with CASTOR1, directly binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Does not directly bind arginine, but binding of arginine to CASTOR1 disrupts the interaction of CASTOR2-containing heterodimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.
Protein Name Cytosolic Arginine Sensor For Mtorc1 Subunit 2
Cellular Arginine Sensor For Mtorc1 Protein 2
Gats-Like Protein 2
Database Links Reactome: R-HSA-9639288
Cellular Localisation Cytoplasm
Cytosol
Alternative Antibody Names Anti-Cytosolic Arginine Sensor For Mtorc1 Subunit 2 antibody
Anti-Cellular Arginine Sensor For Mtorc1 Protein 2 antibody
Anti-Gats-Like Protein 2 antibody
Anti-CASTOR2 antibody
Anti-GATSL1 antibody
Anti-GATSL2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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