产品详情
简单介绍:
Human TRPC6 (Transient Receptor Potential Cation Channel Subfamily C, Member 6) Sandwich ELISA Kit (STJE0012814)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.129ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This TRPC6 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | TRPC6 |
Gene ID: | 7225 |
Uniprot ID: | TRPC6_HUMAN |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | Expressed primarily in placenta, lung, spleen, ovary and small intestine. Expressed in podocytes and is a component of the glomerular slit diaphragm. |
Post Translational Modifications | Phosphorylated by FYN, leading to an increase of TRPC6 channel activity. |
Function | Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion. |
Protein Name | Short Transient Receptor Potential Channel 6 Trpc6 Transient Receptor Protein 6 Trp-6 |
Database Links | Reactome: R-HSA-114508 Reactome: R-HSA-139853 Reactome: R-HSA-3295583 Reactome: R-HSA-418890 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
Alternative ELISA Names | Short Transient Receptor Potential Channel 6 ELISA kit Trpc6 ELISA kit Transient Receptor Protein 6 ELISA kit Trp-6 ELISA kit TRPC6 ELISA kit TRP6 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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