产品详情

  • 产品名称：Human SOX18 (Transcription factor SOX-18) CLIA Kit (STJC0000896)

  • 产品型号：STJC0000896
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human SOX18 (Transcription factor SOX-18) CLIA Kit (STJC0000896)
详情介绍：
Applications: CLIA
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Sensitivity: 18.75pg/mL
Detection Limit: 31.25~2000pg/mL
Short Description: This human SOX18 kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.
Storage Instruction: If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
Assay Time: 3.5h
Detection: Chemiluminescence
Gene Symbol: SOX18
Gene ID: 54345
Uniprot ID: SOX18_HUMAN
Specificity: This kit recognizes Human SOX18 in samples. No significant cross-reactivity or interference between Human SOX18 and analogues was observed.
Sample Type: Serum, plasma and other biological fluids
Tissue Specificity Detected in heart, lung, placenta, skeletal muscle, liver, kidney, spleen, prostate, ovary, msosmall intestine and colon.
Function Transcriptional activator that binds to the consensus sequence 5'-AACAAAG-3' in the promoter of target genes and plays an essential role in embryonic cardiovascular development and lymphangiogenesis. Activates transcription of PROX1 and other genes coding for lymphatic endothelial markers. Plays an essential role in triggering the differentiation of lymph vessels, but is not required for the maintenance of differentiated lymphatic endothelial cells. Plays an important role in postnatal angiogenesis, where it is functionally redundant with SOX17. Interaction with MEF2C enhances transcriptional activation. Besides, required for normal hair development.
Protein Name Transcription Factor Sox-18
Cellular Localisation Nucleus
Alternative CLIA Names Transcription Factor Sox-18 CLIA kit
SOX18 CLIA kit
Specificity This kit recognizes Human SOX18 in samples. No significant cross-reactivity or interference between Human SOX18 and analogues was observed.
Reproducibility Both intra-CV and inter-CV are

Information sourced from Uniprot.org


Item Specifications Storage
Micro CLIA Plate (Dismountable) 96T: 8 wells ×12 strips strips -20℃, 6 months
Reference Standard 96T: 2 vials 48T: 1 vial -20℃, 6 months
Concentrated Biotinylated Detection Ab (100×) 96T: 1 vial, 120 μL 60 μL -20℃, 6 months
Concentrated HRP Conjugate (100×) 96T: 1 vial, 120 μL 60 μL -20℃ (Protect from light), 6 months
Reference Standard & Sample Diluent 1 vial, 20 mL 2-8°C, 6 months
Biotinylated Detection Ab Diluent 1 vial, 14 mL 2-8°C, 6 months
HRP Conjugate Diluent 1 vial, 14 mL 2-8°C, 6 months
Concentrated Wash Buffer (25×) 1 vial, 30 mL 2-8°C, 6 months
Substrate Reagent A 1 vial, 5 mL 2-8℃ (Protect from light)
Substrate Reagent B 1 vial, 5 mL 2-8℃ (Protect from light)
Plate Sealer 5 pieces
Manual 1 copy
Certificate of Analysis 1 copy

Sample Type Range (%) Average Recovery (%)
Serum(n=8) 89-100 94
EDTA plasma(n=8) 90-105 97
Cell culture media(n=8) 92-105 99

Intra-assay Precision Intra-assay Precision Intra-assay Precision Inter-assay Precision Inter-assay Precision Inter-assay Precision
Sample 1.00 2.00 3.00 1.00 2.00 3.00
n 20.00 20.00 20.00 20.00 20.00 20.00
Mean (pg/mL) 102.41 174.44 900.43 98.92 160.50 959.78
Standard deviation 9.43 13.01 88.96 9.08 13.53 108.94
CV (%) 9.21 7.46 9.88 9.18 8.43 11.35
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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