产品详情

  • 产品名称：Anti-CFB antibody (80-420) (STJ115209)

  • 产品型号：STJ115209
  • 产品厂商：ST john's laboratory
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
Anti-CFB antibody (80-420) (STJ115209)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CFB (80-420) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CFB
Gene ID: 629
Uniprot ID: CFAB_HUMAN
Immunogen Region: 80-420
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 80-420 of human Complement factor B (CFB) (NP_001701.2).
Immunogen Sequence: GSWSTLKTQDQKTVRKAECR AIHCPRPHDFENGEYWPRSP YYNVSDEISFHCYDGYTLRG SANRTCQVNGRWSGQTAICD NGAGYCSNPGIPIGTRKVGS QYRLEDSVTYHCSRGLTLRG SQRRTCQEGGSWSGTEPSCQ DSFMYDTPQEVAEAFLSSLT ETIEGVDAEDGHGPGEQQKR KIVLDPSGSMNIYLVLDGSD SIGASNFTGAKKCLVNLIEK VASYGVKPRYGLVTYATYP
Function Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
Protein Name Complement Factor B
C3/C5 Convertase
Glycine-Rich Beta Glycoprotein
Gbg
Pbf2
Properdin Factor B Cleaved Into - Complement Factor B Ba Fragment - Complement Factor B Bb Fragment
Database Links Reactome: R-HSA-173736
Reactome: R-HSA-174577
Reactome: R-HSA-977606
Cellular Localisation Secreted
Alternative Antibody Names Anti-Complement Factor B antibody
Anti-C3/C5 Convertase antibody
Anti-Glycine-Rich Beta Glycoprotein antibody
Anti-Gbg antibody
Anti-Pbf2 antibody
Anti-Properdin Factor B Cleaved Into - Complement Factor B Ba Fragment - Complement Factor B Bb Fragment antibody
Anti-CFB antibody
Anti-BF antibody
Anti-BFD antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
姓名：
电话：
您的需求：
 
网站地图