产品详情
简单介绍:
Anti-CAPRIN2 antibody (88-329) (STJ119491)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-CAPRIN2 (88-329) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CAPRIN2 |
Gene ID: | 65981 |
Uniprot ID: | CAPR2_HUMAN |
Immunogen Region: | 88-329 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 88-329 of CAPRIN2 (NP_001002259.1). |
Immunogen Sequence: | QVNHSQHGESQRALSPLQST LSSAASPSQAYETYIENGLI CLKHKIRNIEKKKLKLEDYK DRLKSGEHLNPDQLEAVEKY EEVLHNLEFAKELQKTFSGL SLDLLKAQKKAQRREHMLKL EAEKKKLRTILQVQYVLQNL TQEHVQKDFKGGLNGAVYLP SKELDYLIKFSKLTCPERNE SLSVEDQMEQSSLYFWDLLE GSEKAVVGTTYKHLKDLLSK LLNSGYFESIPVPKNAKEK |
Tissue Specificity | Detected in all tissues tested with highest levels of expression in brain and spleen. |
Function | Promotes phosphorylation of the Wnt coreceptor LRP6, leading to increased activity of the canonical Wnt signaling pathway. Facilitates constitutive LRP6 phosphorylation by CDK14/CCNY during G2/M stage of the cell cycle, which may potentiate cells for Wnt signaling. May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons. Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation. May be involved in apoptosis. |
Protein Name | Caprin-2 C1q Domain-Containing Protein 1 Cytoplasmic Activation/Proliferation-Associated Protein 2 Gastric Cancer Multidrug Resistance-Associated Protein Protein Eeg-1 Rna Granule Protein 140 |
Cellular Localisation | Isoform 1: Cytoplasm Isoform 2: Mitochondrion Cytoplasm Expressed Throughout The Cytoplasm Isoform 5: Mitochondrion Colocalizes With Aggregated Mitochondria Cell Membrane Peripheral Membrane Protein |
Alternative Antibody Names | Anti-Caprin-2 antibody Anti-C1q Domain-Containing Protein 1 antibody Anti-Cytoplasmic Activation/Proliferation-Associated Protein 2 antibody Anti-Gastric Cancer Multidrug Resistance-Associated Protein antibody Anti-Protein Eeg-1 antibody Anti-Rna Granule Protein 140 antibody Anti-CAPRIN2 antibody Anti-C1QDC1 antibody Anti-EEG1 antibody Anti-KIAA1873 antibody Anti-RNG140 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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