产品详情

  • 产品名称：Anti-CD162/Selplg antibody [4RA10] {AF647} (STJA0001405)

  • 产品型号：STJA0001405
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CD162/Selplg antibody [4RA10] {AF647} (STJA0001405)
详情介绍：
Host: Rat
Applications: FC
Reactivity: Mouse
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Rat monoclonal antibody anti-P-selectin glycoprotein ligand 1 is suitable for use in Flow Cytometry research applications.
Clonality: Monoclonal
Clone ID: 4RA10
Conjugation: AF647
Isotype: IgG1k
Formulation: PBS with 0.05% Proclin300, 1% BSA
Storage Instruction: Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.
Gene Symbol: SelplgUniprot ID=SELPL_MOUSE"
Tissue Specificity Highly expressed in blood, bone marrow, brain, adipose tissue, spleen, and thymus. Also expressed in heart, kidney, liver, muscle, ovary, and stomach.
Post Translational Modifications Displays complex, core-2, sialylated and fucosylated O-linked oligosaccharides, at least some of which appear to contain poly-N-acetyllactosamine with varying degrees of substitution. Mainly disialylated or neutral forms of the core-2 tetrasaccharide, Galbeta1-->4GlcNAcbeta1-->6(Galbeta1-->3)GalNAcOH. The GlcN:GalN ratio is approximately 2:1 and the Man:Fuc ratio 3:5. Contains about 14% fucose with alpha-1,3 linkage present in two forms: One species is a disialylated, monofucosylated glycan, and the other, a monosialylated, trifucosylated glycan with a polylactosamine backbone. The fucosylated forms carry the Lewis antigen and are important for interaction with selectins and for functioning. No sulfated O-glycans. Some N-glycosylation.
Function A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E- and P-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture.
Protein Name P-Selectin Glycoprotein Ligand 1
Psgl-1
Selectin P Ligand
Cd Antigen Cd162
Cellular Localisation Cell Membrane
Single-Pass Membrane Protein
Alternative Antibody Names Anti-P-Selectin Glycoprotein Ligand 1 antibody
Anti-Psgl-1 antibody
Anti-Selectin P Ligand antibody
Anti-Cd Antigen Cd162 antibody
Anti-Selplg antibody
Anti-Selp1 antibody
Anti-Selpl antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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