产品详情

  • 产品名称：Anti-CSNK1E antibody (276-325 aa) (STJ92016)

  • 产品型号：STJ92016
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CSNK1E antibody (276-325 aa) (STJ92016)
详情介绍：
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Casein kinase I isoform epsilon (276-325 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CSNK1E
Gene ID: 102800317/1454
Uniprot ID: KC1E_HUMAN
Immunogen Region: 276-325 aa
Specificity: Casein Kinase I Epsilon Polyclonal Antibody detects endogenous levels of Casein Kinase I Epsilon protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human CKI-epsilon at the amino acid range 276-325
Post Translational Modifications Autophosphorylated. Partially dephosphorylated by PPP5C. May be dephosphorylated by PP1.
Function Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates (Probable). Participates in Wnt signaling. Phosphorylates DVL1. Phosphorylates DVL2. Phosphorylates NEDD9/HEF1. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation.
Protein Name Casein Kinase I Isoform Epsilon
Cki-Epsilon
Ckie
Database Links Reactome: R-HSA-201688
Reactome: R-HSA-2565942
Reactome: R-HSA-380259
Reactome: R-HSA-380270
Reactome: R-HSA-380284
Reactome: R-HSA-380320
Reactome: R-HSA-400253
Reactome: R-HSA-5620912
Reactome: R-HSA-6791226
Reactome: R-HSA-8854518
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-Casein Kinase I Isoform Epsilon antibody
Anti-Cki-Epsilon antibody
Anti-Ckie antibody
Anti-CSNK1E antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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