产品详情
简单介绍:
Mouse ACACa (Acetyl Coenzyme A Carboxylase Alpha) Sandwich ELISA Kit Ready-To-Use (STJE0013209)
详情介绍:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.113ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This ACACa Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | Acaca |
Gene ID: | 107476 |
Uniprot ID: | ACACA_MOUSE |
Immunogen Region: | Ready-To-Use |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | Phosphorylation on Ser-1262 is required for interaction with BRCA1. Phosphorylation at Ser-79 by AMPK inactivates enzyme activity. The biotin cofactor is covalently attached to the central biotinyl-binding domain and is required for the catalytic activity. |
Function | Cytosolic enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosesynthesis. This is a 2 steps reaction starting with the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA. |
Protein Name | Acetyl-Coa Carboxylase 1 Acc1 Acc-Alpha Acetyl-Coa Carboxylase 265 |
Database Links | Reactome: R-MMU-163765 Reactome: -MMU-196780 Reactome: -MMU-200425 Reactome: -MMU-75105 |
Cellular Localisation | Cytoplasm Cytosol |
Alternative ELISA Names | Acetyl-Coa Carboxylase 1 ELISA kit Acc1 ELISA kit Acc-Alpha ELISA kit Acetyl-Coa Carboxylase 265 ELISA kit Acaca ELISA kit Acac ELISA kit Gm738 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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