产品详情
简单介绍:
Mouse ABCC6 (ATP Binding Cassette Transporter C6) Sandwich ELISA Kit (STJE0006825)
详情介绍:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.124ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This ABCC6 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | Abcc6 |
Gene ID: | 27421 |
Uniprot ID: | MRP6_MOUSE |
Sample Type: | tissue homogenates or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | Glycosylated. |
Function | ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. Mediates ATP-dependent transport of glutathione conjugates such as leukotriene-c4 (LTC4) and N-ethylmaleimide S-glutathione (NEM-GS) (in vitro), and an anionic cyclopentapeptide endothelin antagonist, BQ-123. May contribute to regulate the transport of organic compounds in testes across the blood-testis-barrier. Mediates the release of nucleoside triphosphates, predominantly ATP, into the circulation, where it is rapidly converted into AMP and the mineralization inhibitor inorganic pyrophosphate (PPi) by the ecto-enzyme ectonucleotide pyrophosphatase phosphodiesterase 1 (ENPP1), therefore playing a role in PPi homeostasis. |
Protein Name | Atp-Binding Cassette Sub-Family C Member 6 Multidrug Resistance-Associated Protein 6 |
Database Links | Reactome: R-MMU-382556 |
Cellular Localisation | Basolateral Cell Membrane Multi-Pass Membrane Protein Basal Cell Membrane |
Alternative ELISA Names | Atp-Binding Cassette Sub-Family C Member 6 ELISA kit Multidrug Resistance-Associated Protein 6 ELISA kit Abcc6 ELISA kit Mrp6 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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