产品详情
简单介绍:
Anti-CPNE1 antibody (STJA0007737)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Copine-1 is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CPNE1 |
Gene ID: | 8904 |
Uniprot ID: | CPNE1_HUMAN |
Specificity: | This antibody detects endogenous levels of CPNE1 at Human, Mouse |
Immunogen: | Synthesized peptide derived from human CPNE1 |
Function | Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Involved in the TNF-alpha receptor signaling pathway in a calcium-dependent manner. Exhibits calcium-dependent phospholipid binding properties. Plays a role in neuronal progenitor cell differentiation.induces neurite outgrowth via a AKT-dependent signaling cascade and calcium-independent manner. May recruit target proteins to the cell membrane in a calcium-dependent manner. May function in membrane trafficking. Involved in TNF-alpha-induced NF-kappa-B transcriptional repression by inducing endoprotease processing of the transcription factor NF-kappa-B p65/RELA subunit. Also induces endoprotease processing of NF-kappa-B p50/NFKB1, p52/NFKB2, RELB and REL. |
Protein Name | Copine-1 Chromobindin 17 Copine I |
Database Links | Reactome: R-HSA-1483206 Reactome: R-HSA-6798695 |
Cellular Localisation | Nucleus Cytoplasm Cell Membrane Translocates To The Cell Membrane In A Calcium-Dependent Manner |
Alternative Antibody Names | Anti-Copine-1 antibody Anti-Chromobindin 17 antibody Anti-Copine I antibody Anti-CPNE1 antibody Anti-CPN1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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