产品详情

  • 产品名称：Anti-CD107a antibody [1D4B] {PE/Cyanine5} (STJA0004266)

  • 产品型号：STJA0004266
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CD107a antibody [1D4B] {PE/Cyanine5} (STJA0004266)
详情介绍：
Host: Rat
Applications: FC
Reactivity: Mouse
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Rat monoclonal antibody anti-Lysosome-Associated Membrane Glycoprotein 1
Clonality: Monoclonal
Clone ID: 1D4B
Conjugation: PE/Cyanine5
Isotype: IgG2ak
Formulation: PBS with 0.05% Proclin300, 1% BSA
Storage Instruction: Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.
Gene Symbol: Lamp1
Gene ID: 16783
Uniprot ID: LAMP1_MOUSE
Post Translational Modifications O- and N-glycosylated.some of the N-glycans attached to LAMP-1 are polylactosaminoglycans.
Function Lysosomal membrane glycoprotein which plays an important role in lysosome biogenesis, lysosomal pH regulation, autophagy and cholesterol homeostasis. Acts as an important regulator of lysosomal lumen pH regulation by acting as a direct inhibitor of the proton channel TMEM175, facilitating lysosomal acidification for optimal hydrolase activity. Also plays an important role in NK-cells cytotoxicity. Mechanistically, participates in cytotoxic granule movement to the cell surface and perforin trafficking to the lytic granule. In addition, protects NK-cells from degranulation-associated damage induced by their own cytotoxic granule content. Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.
Protein Name Lysosome-Associated Membrane Glycoprotein 1
Lamp-1
Lysosome-Associated Membrane Protein 1
120 Kda Lysosomal Membrane Glycoprotein
Cd107 Antigen-Like Family Member A
Lgp-120
Lysosomal Membrane Glycoprotein A
Lgp-A
P2b
Cd Antigen Cd107a
Database Links Reactome: R-MMU-6798695
Cellular Localisation Lysosome Membrane
Single-Pass Type I Membrane Protein
Endosome Membrane
Late Endosome Membrane
Cell Membrane
Cytolytic Granule Membrane
This Protein Shuttles Between Lysosomes
Endosomes
And The Plasma Membrane
Colocalizes With Osbpl1a At The Late Endosome
Alternative Antibody Names Anti-Lysosome-Associated Membrane Glycoprotein 1 antibody
Anti-Lamp-1 antibody
Anti-Lysosome-Associated Membrane Protein 1 antibody
Anti-120 Kda Lysosomal Membrane Glycoprotein antibody
Anti-Cd107 Antigen-Like Family Member A antibody
Anti-Lgp-120 antibody
Anti-Lysosomal Membrane Glycoprotein A antibody
Anti-Lgp-A antibody
Anti-P2b antibody
Anti-Cd Antigen Cd107a antibody
Anti-Lamp1 antibody
Anti-Lamp-1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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