产品详情
简单介绍:
Anti-CoA synthase antibody (465-564) [S2MR] (STJ11102722)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit monoclonal antibody anti-CoA synthase (COASY ) (465-564) is suitable for use in Western Blot research applications. |
Clonality: | Monoclonal |
Clone ID: | S2MR |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:1000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | COASY |
Gene ID: | 80347 |
Uniprot ID: | COASY_HUMAN |
Immunogen Region: | 465-564 |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 465-564 of human CoA synthase (COASY ) (Q13057). |
Immunogen Sequence: | RVCVIDAAVLLEAGWQNLVH EVWTAVIPETEAVRRIVERD GLSEAAAQSRLQSQMSGQQL VEQSHVVLSTLWEPHITQRQ VEKAWALLQKRIPKTHQALD |
Tissue Specificity | Expressed in all tissues examined including brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocyte. Lowest expression in peripheral blood leukocytes and highest in kidney and liver. Isoform 2 is expressed mainly in the brain. |
Function | Bifunctional enzyme that catalyzes the fourth and fifth sequential steps of CoA biosesynthetic pathway. The fourth reaction is catalyzed by the phosphopantetheine adenylyltransferase, coded by the coaD domain.the fifth reaction is catalyzed by the dephospho-CoA kinase, coded by the coaE domain. May act as a point of CoA biosesynthesis regulation. |
Protein Name | Bifunctional Coenzyme A Synthase Coa Synthase Nbp Pov-2 Includes - Phosphopantetheine Adenylyltransferase Dephospho-Coa Pyrophosphorylase Pantetheine-Phosphate Adenylyltransferase Ppat - Dephospho-Coa Kinase Dpck Dephosphocoenzyme A Kinase Dpcoak |
Database Links | Reactome: R-HSA-196783 |
Cellular Localisation | Cytoplasm Mitochondrion Matrix The Protein Is Mainly Present In The Mitochondrial Matrix Probably Anchored To The Inner Mitochondrial Membrane But Is Also Present In Cell Lysate |
Alternative Antibody Names | Anti-Bifunctional Coenzyme A Synthase antibody Anti-Coa Synthase antibody Anti-Nbp antibody Anti-Pov-2 Includes - Phosphopantetheine Adenylyltransferase antibody Anti-Dephospho-Coa Pyrophosphorylase antibody Anti-Pantetheine-Phosphate Adenylyltransferase antibody Anti-Ppat - Dephospho-Coa Kinase antibody Anti-Dpck antibody Anti-Dephosphocoenzyme A Kinase antibody Anti-Dpcoak antibody Anti-COASY antibody Anti-PSEC0106 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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