产品详情
简单介绍:
Human TJP2 (Tight Junction Protein 2) Sandwich ELISA Kit Ready-To-Use (STJE0019005)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.053ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This TJP2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | TJP2 |
Gene ID: | 9414 |
Uniprot ID: | ZO2_HUMAN |
Immunogen Region: | Ready-To-Use |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | This protein is found in epithelial cell junctions. Isoform A1 is abundant in the heart and brain. Detected in brain and skeletal muscle. It is present almost exclusively in normal tissues. Isoform C1 is expressed at high level in the kidney, pancreas, heart and placenta. Not detected in brain and skeletal muscle. Found in normal as well as in most neoplastic tissues. |
Post Translational Modifications | |
Function | Plays a role in tight junctions and adherens junctions. Acts as a positive regulator of RANKL-induced osteoclast differentiation, potentially via mediating downstream transcriptional activity. |
Protein Name | Tight Junction Protein Zo-2 Tight Junction Protein 2 Zona Occludens Protein 2 Zonula Occludens Protein 2 |
Database Links | Reactome: R-HSA-2028269 Reactome: R-HSA-351906 Reactome: R-HSA-8980692 Reactome: R-HSA-9013026 Reactome: R-HSA-9013106 |
Cellular Localisation | Cell Junction Adherens Junction Cell Membrane Peripheral Membrane Protein Cytoplasmic Side Tight Junction Nucleus Also Nuclear Under Environmental Stress Conditions And In Migratory Endothelial Cells And Subconfluent Epithelial Cell Cultures |
Alternative ELISA Names | Tight Junction Protein Zo-2 ELISA kit Tight Junction Protein 2 ELISA kit Zona Occludens Protein 2 ELISA kit Zonula Occludens Protein 2 ELISA kit TJP2 ELISA kit X104 ELISA kit ZO2 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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