产品详情
简单介绍:
Human THSD7A (Thrombospondin Type I Domain Containing Protein 7A) Sandwich ELISA Kit (STJE0012566)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.058ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This THSD7A Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | THSD7A |
Gene ID: | 221981 |
Uniprot ID: | THS7A_HUMAN |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | Detected on kidney podocytes along the glomerular capillary wall (at protein level). |
Post Translational Modifications | Proteolytic cleavage in the extracellular region generates a 210 kDa soluble form. Extensively N-glycosylated. |
Function | Thrombospondin type-1 domain-containing protein 7A: Plays a role in actin cytoskeleton rearrangement. Thrombospondin type-1 domain-containing protein 7A, soluble form: The soluble form promotes endothelial cell migration and filopodia formation during sprouting angiogenesis via a FAK-dependent mechanism. |
Protein Name | Thrombospondin Type-1 Domain-Containing Protein 7a Cleaved Into - Thrombospondin Type-1 Domain-Containing Protein 7a - Soluble Form |
Database Links | Reactome: R-HSA-5083635 Reactome: R-HSA-5173214 |
Cellular Localisation | Thrombospondin Type-1 Domain-Containing Protein 7a: Cell Membrane Single-Pass Type I Membrane Protein Cell Projection Detected On Podocyte Foot Processes Thrombospondin Type-1 Domain-Containing Protein 7a Soluble Form: Secreted Proteolytic Cleavage In The Extracellular Region Generates A 210 Kda Soluble Form |
Alternative ELISA Names | Thrombospondin Type-1 Domain-Containing Protein 7a Cleaved Into - Thrombospondin Type-1 Domain-Containing Protein 7a - Soluble Form ELISA kit THSD7A ELISA kit KIAA0960 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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