产品详情
简单介绍:
Anti-CHRNA4 antibody (29-242) (STJ111101)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-CHRNA4 (29-242) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CHRNA4 |
Gene ID: | 1137 |
Uniprot ID: | ACHA4_HUMAN |
Immunogen Region: | 29-242 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-242 of human ACHA4 (P43681). |
Immunogen Sequence: | HVETRAHAEERLLKKLFSGY NKWSRPVANISDVVLVRFGL SIAQLIDVDEKNQMMTTNVW VKQEWHDYKLRWDPADYENV TSIRIPSELIWRPDIVLYNN ADGDFAVTHLTKAHLFHDGR VQWTPPAIYKSSCSIDVTFF PFDQQNCTMKFGSWTYDKAK IDLVNMHSRVDQLDFWESGE WVIVDAVGTYNTRKYECCAE IYPDITYAFVIRRL |
Function | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions. |
Protein Name | Neuronal Acetylcholine Receptor Subunit Alpha-4 |
Database Links | Reactome: R-HSA-629587 Reactome: R-HSA-629594 Reactome: R-HSA-629597 |
Cellular Localisation | Postsynaptic Cell Membrane Multi-Pass Membrane Protein Cell Membrane Lipid-Anchor |
Alternative Antibody Names | Anti-Neuronal Acetylcholine Receptor Subunit Alpha-4 antibody Anti-CHRNA4 antibody Anti-NACRA4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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