产品详情
简单介绍:
Anti-CHRNA3 antibody (32-240) (STJ111103)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-CHRNA3 (32-240) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CHRNA3 |
Gene ID: | 1136 |
Uniprot ID: | ACHA3_HUMAN |
Immunogen Region: | 32-240 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 32-240 of human CHRNA3 (NP_000734.2). |
Immunogen Sequence: | SEAEHRLFERLFEDYNEIIR PVANVSDPVIIHFEVSMSQL VKVDEVNQIMETNLWLKQIW NDYKLKWNPSDYGGAEFMRV PAQKIWKPDIVLYNNAVGDF QVDDKTKALLKYTGEVTWIP PAIFKSSCKIDVTYFPFDYQ NCTMKFGSWSYDKAKIDLVL IGSSMNLKDYWESGEWAIIK APGYKHDIKYNCCEEIYPDI TYSLYIRRL |
Function | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
Protein Name | Neuronal Acetylcholine Receptor Subunit Alpha-3 |
Database Links | Reactome: R-HSA-629587 Reactome: R-HSA-629594 Reactome: R-HSA-629597 |
Cellular Localisation | Postsynaptic Cell Membrane Multi-Pass Membrane Protein Cell Membrane |
Alternative Antibody Names | Anti-Neuronal Acetylcholine Receptor Subunit Alpha-3 antibody Anti-CHRNA3 antibody Anti-NACHRA3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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