产品详情
简单介绍:
Anti-CHRNA1 antibody (171-220 aa) (STJ97250)
详情介绍:
Host: | Rabbit |
Applications: | WB/IF/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Acetylcholine receptor subunit alpha (171-220 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000 ELISA 1:5000 IF 1:100-300 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CHRNA1 |
Gene ID: | 1134 |
Uniprot ID: | ACHA_HUMAN |
Immunogen Region: | 171-220 aa |
Specificity: | AChR Alpha 1 Polyclonal Antibody detects endogenous levels of AChR Alpha 1 protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the Internal region of human CHRNA1 at the amino acid range 171-220 |
Function | Isoform 1: Upon acetylcholine binding, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Isoform 2: Non functional acetylcholine receptor alpha subunit which is not integrated into functional acetylcholine-gated cation-selective channels. |
Protein Name | Acetylcholine Receptor Subunit Alpha |
Database Links | Reactome: R-HSA-629594 Reactome: R-HSA-629597 |
Cellular Localisation | Postsynaptic Cell Membrane Multi-Pass Membrane Protein Cell Membrane |
Alternative Antibody Names | Anti-Acetylcholine Receptor Subunit Alpha antibody Anti-CHRNA1 antibody Anti-ACHRA antibody Anti-CHNRA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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