产品详情
简单介绍:
Anti-CES2 antibody (310-410) (STJ23101)
详情介绍:
Host: | Rabbit |
Applications: | WB/IF |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-CES2 (310-410) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 IF/ICC 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CES2 |
Gene ID: | 8824 |
Uniprot ID: | EST2_HUMAN |
Immunogen Region: | 310-410 |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 310-410 of human CES2 (NP_003860.3). |
Immunogen Sequence: | IPGVVDGVFLPRHPQELLAS ADFQPVPSIVGVNNNEFGWL IPKVMRIYDTQKEMDREASQ AALQKMLTLLMLPPTFGDLL REEYIGDNGDPQTLQAQFQE M |
Tissue Specificity | Preferentially expressed in intestine with moderate expression in liver. Within the intestine, highest expression is found in small intestine with lower expression in colon and rectum. |
Post Translational Modifications | Glycosylated. |
Function | Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine. Hydrolyzes aspirin, substrates with large alcohol group and small acyl group and endogenous lipids such as triacylglycerol. Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes of 2-arachidonoylglycerol and prostaglandins. |
Protein Name | Cocaine Esterase Carboxylesterase 2 Ce-2 Hce-2 Methylumbelliferyl-Acetate Deacetylase 2 |
Database Links | Reactome: R-HSA-211945 Reactome: R-HSA-9749641 |
Cellular Localisation | Endoplasmic Reticulum Lumen |
Alternative Antibody Names | Anti-Cocaine Esterase antibody Anti-Carboxylesterase 2 antibody Anti-Ce-2 antibody Anti-Hce-2 antibody Anti-Methylumbelliferyl-Acetate Deacetylase 2 antibody Anti-CES2 antibody Anti-ICE antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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