产品详情

  • 产品名称：Anti-CERS5 antibody (1-100) (STJ119360)

  • 产品型号：STJ119360
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CERS5 antibody (1-100) (STJ119360)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CERS5 (1-100) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CERS5
Gene ID: 91012
Uniprot ID: CERS5_HUMAN
Immunogen Region: 1-100
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CERS5 (NP_001268660.1).
Immunogen Sequence: MMKPRPKRFIAKPCALCIGI EDSGPYQAQPNAILEKVFIS ITKYPDKKRLEGLSKQLDWN VRKIQCWFRHRRNQDKPPTL TKFCESMWRFTFYLCIFCYG
Post Translational Modifications Phosphorylated at the C-terminus by CK2.
Function Ceramide synthase that catalyzes the transfer of the acyl chain from acyl-CoA to a sphingoid base, with high selectivity toward palmitoyl-CoA (hexadecanoyl-CoA.C16:0-CoA). Can use other acyl donors, but with less efficiency. N-acylates sphinganine and sphingosine bases to form dihydroceramides and ceramides in de novo synthesis and salvage pathways, respectively. Plays a role in de novo ceramide synthesis and surfactant homeostasis in pulmonary epithelia.
Protein Name Ceramide Synthase 5
Cers5
Lag1 Longevity Assurance Homolog 5
Sphingoid Base N-Palmitoyltransferase Cers5
Sphingosine N-Acyltransferase Cers5
Database Links Reactome: R-HSA-1660661
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Ceramide Synthase 5 antibody
Anti-Cers5 antibody
Anti-Lag1 Longevity Assurance Homolog 5 antibody
Anti-Sphingoid Base N-Palmitoyltransferase Cers5 antibody
Anti-Sphingosine N-Acyltransferase Cers5 antibody
Anti-CERS5 antibody
Anti-LASS5 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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