产品详情

  • 产品名称：Human S100A4 (S100 Calcium Binding Protein A4) Sandwich ELISA Kit (STJE0011979)

  • 产品型号：STJE0011979
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human S100A4 (S100 Calcium Binding Protein A4) Sandwich ELISA Kit (STJE0011979)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 29pg/mL
Detection Limit: 78.1-5000pg/mL
Short Description: This S100A4 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: S100A4
Gene ID: 6275
Uniprot ID: S10A4_HUMAN
Sample Type: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity Ubiquitously expressed.
Post Translational Modifications
Function Calcium-binding protein that plays a role in various cellular processes including motility, angiogenesis, cell differentiation, apoptosis, and autophagy. Increases cell motility and invasiveness by interacting with non-muscle myosin heavy chain (NMMHC) IIA/MYH9. Mechanistically, promotes filament depolymerization and increases the amount of soluble myosin-IIA, resulting in the formation of stable protrusions facilitating chemotaxis. Modulates also the pro-apoptotic function of TP53 by binding to its C-terminal transactivation domain within the nucleus and reducing its protein levels. Within the extracellular space, stimulates cytokine production including granulocyte colony-stimulating factor and CCL24 from T-lymphocytes. In addition, stimulates T-lymphocyte chemotaxis by acting as a chemoattractant complex with PGLYRP1 that promotes lymphocyte migration via CCR5 and CXCR3 receptors.
Protein Name Protein S100-A4
Calvasculin
Metastasin
Placental Calcium-Binding Protein
Protein Mts1
S100 Calcium-Binding Protein A4
Database Links
Cellular Localisation Secreted
Nucleus
Cytoplasm
Alternative ELISA Names Protein S100-A4 ELISA kit
Calvasculin ELISA kit
Metastasin ELISA kit
Placental Calcium-Binding Protein ELISA kit
Protein Mts1 ELISA kit
S100 Calcium-Binding Protein A4 ELISA kit
S100A4 ELISA kit
CAPL ELISA kit
MTS1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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