产品详情

  • 产品名称：Human RAB8B (RAB8B, Member RAS Oncogene Family) Sandwich ELISA Kit (STJE0011806)

  • 产品型号：STJE0011806
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human RAB8B (RAB8B, Member RAS Oncogene Family) Sandwich ELISA Kit (STJE0011806)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.055ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This RAB8B Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: RAB8B
Gene ID: 51762
Uniprot ID: RAB8B_HUMAN
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications Phosphorylation of Thr-72 in the switch II region by LRRK2 prevents the association of RAB regulatory proteins, including CHM, CHML and RAB GDP dissociation inhibitors GDI1 and GDI2.
Function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells. May participate in the export of a subset of neosynthesized proteins through a Rab8-Rab10-Rab11-dependent endososomal export route.
Protein Name Ras-Related Protein Rab-8b
Database Links Reactome: R-HSA-8854214
Reactome: R-HSA-8873719
Reactome: R-HSA-8876198
Cellular Localisation Cell Membrane
Lipid-Anchor
Cytoplasmic Side
Cytoplasmic Vesicle
Phagosome
Phagosome Membrane
Endosome Membrane
Recruited To Phagosomes Containing S
Aureus Or M
Tuberculosis
Colocalized With Mical1
Graf1/Arhgap26 And Graf2/Arhgap10 On Endosomal Tubules
Alternative ELISA Names Ras-Related Protein Rab-8b ELISA kit
RAB8B ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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