产品详情

  • 产品名称：Anti-CD55 antibody [143-30] (STJ16101888)

  • 产品型号：STJ16101888
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CD55 antibody [143-30] (STJ16101888)
详情介绍：
Host: Mouse
Applications: FC/WB/IF/IHC
Reactivity: Human/Pig
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-CD55 is suitable for use in Flow Cytometry, Western Blot, Immunofluorescence and Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: 143-30
Conjugation: Unconjugated
Isotype: IgG1k
Formulation: PBS with 0.02% Sodium Azide.
Purification: Affinity purified from tissue culture.
Concentration: Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL.
Dilution Range: Flow cytometry (0, 5-1, 0 µg/million cells in 0, 1 ml). Immunoblotting (1-2 µg/ml). Immunofluorescence (0, 5-1, 0 µg/ml).Immunohistology (1-2 µg/ml for 30 min at RT; an appropriate antigen retrievals method for staining of formalin-fixed tissues has n
Storage Instruction: Store for up to 1 year at 2-8°C upon receipt.
Gene Symbol: CD55
Gene ID: 1604
Uniprot ID: DAF_HUMAN
Immunogen: A BALB/c mouse was immunized with stimulated human leucocytes. Fusion partner: NS-1.
Post Translational Modifications The Ser/Thr-rich domain is heavily O-glycosylated.
Function This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage. (Microbial infection) Acts as a receptor for Coxsackievirus A21, coxsackieviruses B1, B3 and B5. (Microbial infection) Acts as a receptor for Human enterovirus 70 and D68 (Probable). (Microbial infection) Acts as a receptor for Human echoviruses 6, 7, 11, 12, 20 and 21.
Protein Name Complement Decay-Accelerating Factor
Cd Antigen Cd55
Database Links Reactome: R-HSA-373080
Reactome: R-HSA-6798695
Reactome: R-HSA-6807878
Reactome: R-HSA-977606
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Cell Membrane
Lipid-Anchor
Gpi-Anchor
Isoform 3: Secreted
Isoform 4: Secreted
Isoform 5: Secreted
Isoform 6: Cell Membrane
Isoform 7: Cell Membrane
Alternative Antibody Names Anti-Complement Decay-Accelerating Factor antibody
Anti-Cd Antigen Cd55 antibody
Anti-CD55 antibody
Anti-CR antibody
Anti-DAF antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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