产品详情
简单介绍:
Human PANX1 (Pannexin-1) Sandwich ELISA Kit (STJE0011268)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.060ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This PANX1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | PANX1 |
Gene ID: | 24145 |
Uniprot ID: | PANX1_HUMAN |
Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
Tissue Specificity | Widely expressed. Highest expression is observed in oocytes and brain. Detected at very low levels in sperm cells. |
Post Translational Modifications | S-nitrosylation inhibits channel currents and ATP release. N-glycosylation may play a role in cell surface targeting. Exists in three glycosylation states: non-glycosylated (GLY0), high-mannose glycosylated (GLY1), and fully mature glycosylated (GLY2). |
Function | Structural component of the gap junctions and the hemichannels involved in the ATP release and nucleotide permeation. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis. Plays a critical role in oogenesis. |
Protein Name | Pannexin-1 |
Database Links | Reactome: R-HSA-112303 Reactome: R-HSA-844456 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Cell Junction Gap Junction Endoplasmic Reticulum Membrane |
Alternative ELISA Names | Pannexin-1 ELISA kit PANX1 ELISA kit MRS1 ELISA kit UNQ2529 ELISA kit PRO6028 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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