产品详情

  • 产品名称：Anti-Cenexin1/ODF2 antibody (730-829) [S7MR] (STJ11103527)

  • 产品型号：STJ11103527
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-Cenexin1/ODF2 antibody (730-829) [S7MR] (STJ11103527)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Cenexin1/ODF2 (730-829) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S7MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ODF2
Gene ID: 4957
Uniprot ID: ODFP2_HUMAN
Immunogen Region: 730-829
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 730-829 of human Cenexin1/ODF2 (Q5BJF6).
Immunogen Sequence: KEHALSKERAAQNKILDLET QLSRTKTELSQLRRSRDDAD RRYQSRLQDLKDRLEQSEST NRSMQNYVQFLKSSYANVFG DGPYSTFLTSSPIRSRSPPA
Tissue Specificity Testis-specific (at protein level). Highly expressed in cytoplasm of step 2 round spermatids. Detected in the middle piece and extends to about half the principal piece of the sperm tails.
Post Translational Modifications Tyrosine phosphorylated. Phosphorylated by TSSK4 on Ser-95.
Function Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpsiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly.
Protein Name Outer Dense Fiber Protein 2
Cenexin
Outer Dense Fiber Of Sperm Tails Protein 2
Database Links Reactome: R-HSA-2565942
Reactome: R-HSA-380259
Reactome: R-HSA-380270
Reactome: R-HSA-380284
Reactome: R-HSA-380320
Reactome: R-HSA-5620912
Reactome: R-HSA-8854518
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Cell Projection
Cilium
Centriole
Spindle Pole
Flagellum
Localized At The Microtubule Organizing Centers In Interphase And Spindle Poles In Mitosis
Localized At The Distal/Subdistal Appendages Of Mother Centrioles
Alternative Antibody Names Anti-Outer Dense Fiber Protein 2 antibody
Anti-Cenexin antibody
Anti-Outer Dense Fiber Of Sperm Tails Protein 2 antibody
Anti-ODF2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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