产品详情

  • 产品名称：Human PRDX1 (Peroxiredoxin 1) Sandwich ELISA Kit (STJE0011643)

  • 产品型号：STJE0011643
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human PRDX1 (Peroxiredoxin 1) Sandwich ELISA Kit (STJE0011643)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.126ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This PRDX1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: PRDX1
Gene ID: 5052
Uniprot ID: PRDX1_HUMAN
Sample Type: serum, plasma, tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications Phosphorylated on Thr-90 during the M-phase, which leads to a more than 80% decrease in enzymatic activity. The enzyme can be inactivated by further oxidation of the cysteine sulfenic acid (C(P)-SOH) to sulphinic acid (C(P)-SO2H) instead of its condensation to a disulfide bond. It can be reactivated by forming a transient disulfide bond with sulfiredoxin SRXN1, which reduces the cysteine sulfinic acid in an ATP- and Mg-dependent manner.
Function Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation.
Protein Name Peroxiredoxin-1
Natural Killer Cell-Enhancing Factor A
Nkef-A
Proliferation-Associated Gene Protein
Pag
Thioredoxin Peroxidase 2
Thioredoxin-Dependent Peroxide Reductase 2
Thioredoxin-Dependent Peroxiredoxin 1
Database Links Reactome: R-HSA-3299685
Reactome: R-HSA-5628897
Reactome: R-HSA-8862803
Reactome: R-HSA-9818027
Cellular Localisation Cytoplasm
Melanosome
Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv
Alternative ELISA Names Peroxiredoxin-1 ELISA kit
Natural Killer Cell-Enhancing Factor A ELISA kit
Nkef-A ELISA kit
Proliferation-Associated Gene Protein ELISA kit
Pag ELISA kit
Thioredoxin Peroxidase 2 ELISA kit
Thioredoxin-Dependent Peroxide Reductase 2 ELISA kit
Thioredoxin-Dependent Peroxiredoxin 1 ELISA kit
PRDX1 ELISA kit
PAGA ELISA kit
PAGB ELISA kit
TDPX2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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