产品详情

  • 产品名称：Human PDE1C (Phosphodiesterase 1C, Calmodulin Dependent) Sandwich ELISA Kit (STJE0011338)

  • 产品型号：STJE0011338
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human PDE1C (Phosphodiesterase 1C, Calmodulin Dependent) Sandwich ELISA Kit (STJE0011338)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.055ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This PDE1C Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: PDE1C
Gene ID: 5137
Uniprot ID: PDE1C_HUMAN
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Isoform PDE1C2 is present in the heart and brain and, at lower levels in the lung, liver, kidney and skeletal muscle. Isoform PDE1C1 is expressed in the heart and brain and, at lower levels in lung. Also expressed at low levels in uterus and testis.
Post Translational Modifications
Function Calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP. Modulates the amplitude and duration of the cAMP signal in sensory cilia in response to odorant stimulation, hence contributing to the generation of action potentials. Regulates smooth muscle cell proliferation. Regulates the stability of growth factor receptors, including PDGFRB (Probable).
Protein Name Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1c
Cam-Pde 1c
Hcam3
Database Links Reactome: R-HSA-111957
Cellular Localisation Lysosome
Alternative ELISA Names Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1c ELISA kit
Cam-Pde 1c ELISA kit
Hcam3 ELISA kit
PDE1C ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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