产品详情
简单介绍:
Human OSMR (Oncostatin-M-specific receptor subunit beta) CLIA Kit (STJC0000940)
详情介绍:
Applications: | CLIA |
Reactivity: | Human |
Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Sensitivity: | 18.75pg/mL |
Detection Limit: | 31.25~2000pg/mL |
Short Description: | This human OSMR kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes. |
Storage Instruction: | If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual. |
Assay Time: | 3.5h |
Detection: | Chemiluminescence |
Gene Symbol: | OSMR |
Gene ID: | 9180 |
Uniprot ID: | OSMR_HUMAN |
Specificity: | This kit recognizes Human OSMR in samples. No significant cross-reactivity or interference between Human OSMR and analogues was observed. |
Sample Type: | Serum, plasma and other biological fluids |
Tissue Specificity | Expressed in keratinocytes (at protein level). Expressed at relatively high levels in all neural cells as well as fibroblast and epithelial cells. |
Function | Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events. |
Protein Name | Oncostatin-M-Specific Receptor Subunit Beta Interleukin-31 Receptor Subunit Beta Il-31 Receptor Subunit Beta Il-31r Subunit Beta Il-31r-Beta Il-31rb |
Database Links | Reactome: R-HSA-6788467 |
Cellular Localisation | Membrane Single-Pass Type I Membrane Protein |
Alternative CLIA Names | Oncostatin-M-Specific Receptor Subunit Beta CLIA kit Interleukin-31 Receptor Subunit Beta CLIA kit Il-31 Receptor Subunit Beta CLIA kit Il-31r Subunit Beta CLIA kit Il-31r-Beta CLIA kit Il-31rb CLIA kit OSMR CLIA kit OSMRB CLIA kit |
Specificity | This kit recognizes Human OSMR in samples. No significant cross-reactivity or interference between Human OSMR and analogues was observed. |
Reproducibility | Both intra-CV and inter-CV are |
Information sourced from Uniprot.org
Micro CLIA Plate (Dismountable) | 96T: 8 wells ×12 strips strips | -20℃, 6 months |
Reference Standard | 96T: 2 vials 48T: 1 vial | -20℃, 6 months |
Concentrated Biotinylated Detection Ab (100×) | 96T: 1 vial, 120 μL 60 μL | -20℃, 6 months |
Concentrated HRP Conjugate (100×) | 96T: 1 vial, 120 μL 60 μL | -20℃ (Protect from light), 6 months |
Reference Standard & Sample Diluent | 1 vial, 20 mL | 2-8°C, 6 months |
Biotinylated Detection Ab Diluent | 1 vial, 14 mL | 2-8°C, 6 months |
HRP Conjugate Diluent | 1 vial, 14 mL | 2-8°C, 6 months |
Concentrated Wash Buffer (25×) | 1 vial, 30 mL | 2-8°C, 6 months |
Substrate Reagent A | 1 vial, 5 mL | 2-8℃ (Protect from light) |
Substrate Reagent B | 1 vial, 5 mL | 2-8℃ (Protect from light) |
Plate Sealer | 5 pieces | |
Manual | 1 copy | |
Certificate of Analysis | 1 copy |
Serum(n=8) | 100-116 | 106 |
EDTA plasma(n=8) | 85-101 | 92 |
Cell culture media(n=8) | 93-104 | 98 |
Sample | 1.00 | 2.00 | 3.00 | 1.00 | 2.00 | 3.00 |
n | 20.00 | 20.00 | 20.00 | 20.00 | 20.00 | 20.00 |
Mean (pg/mL) | 104.61 | 243.26 | 725.40 | 105.97 | 257.71 | 754.98 |
Standard deviation | 10.54 | 28.17 | 61.08 | 11.01 | 28.81 | 53.68 |
CV (%) | 10.08 | 11.58 | 8.42 | 10.39 | 11.18 | 7.11 |
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