产品详情
简单介绍:
Human NTCP (Na+ Taurocholate Cotransporting Polypeptide) Sandwich ELISA Kit Ready-To-Use (STJE0017512)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.27ng/mL |
Detection Limit: | 0.781-50ng/mL |
Short Description: | This NTCP Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | SLC10A1 |
Gene ID: | 6554 |
Uniprot ID: | NTCP_HUMAN |
Immunogen Region: | Ready-To-Use |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | Expressed in liver. Expressed in placental trophoblasts. |
Post Translational Modifications | |
Function | As a major transporter of conjugated bile salts from plasma into the hepatocyte, it plays a key role in the enterohepatic circulation of bile salts necessary for the solubilization and absorption of dietary fat and fat-soluble vitamins. It is strictly dependent on the extracellular presence of sodium. It exhibits broad substrate specificity and transports various bile acids, such as taurocholate, cholate, as well as non-bile acid organic compounds, such as estrone sulfate. Works collaboratively with the ileal transporter (NTCP2), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation. (Microbial infection) Acts as a receptor for hepatitis B virus. |
Protein Name | Hepatic Sodium/Bile Acid Cotransporter Cell Growth-Inhibiting Gene 29 Protein Na(+/Bile Acid Cotransporter Na(+/Taurocholate Transport Protein Sodium/Taurocholate Cotransporting Polypeptide Ntcp Solute Carrier Family 10 Member 1 Slc10a1 |
Database Links | Reactome: R-HSA-159418 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
Alternative ELISA Names | Hepatic Sodium/Bile Acid Cotransporter ELISA kit Cell Growth-Inhibiting Gene 29 Protein ELISA kit Na(+/Bile Acid Cotransporter ELISA kit Na(+/Taurocholate Transport Protein ELISA kit Sodium/Taurocholate Cotransporting Polypeptide ELISA kit Ntcp ELISA kit Solute Carrier Family 10 Member 1 ELISA kit Slc10a1 ELISA kit SLC10A1 ELISA kit NTCP ELISA kit GIG29 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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