产品详情
简单介绍:
Anti-CD28 antibody [CD28.2] {PE/Cyanine5} (STJA0002116)
详情介绍:
Host: | Mouse |
Applications: | FC |
Reactivity: | Human |
Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Short Description: | Mouse monoclonal antibody anti-T-cell-specific surface glycoprotein CD28 is suitable for use in Flow Cytometry research applications. |
Clonality: | Monoclonal |
Clone ID: | CD28.2 |
Conjugation: | PE/Cyanine5 |
Isotype: | IgG1k |
Formulation: | PBS with 0.05% Proclin300, 1% BSA |
Storage Instruction: | Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
Gene Symbol: | CD28 |
Gene ID: | 940 |
Uniprot ID: | CD28_HUMAN |
Tissue Specificity | Expressed in T-cells and plasma cells, but not in less mature B-cells. |
Post Translational Modifications | CD40LG induces tyrosine phosphorylation of isoform 3. |
Function | Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation. Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells. |
Protein Name | T-Cell-Specific Surface Glycoprotein Cd28 Tp44 Cd Antigen Cd28 |
Database Links | Reactome: R-HSA-1257604 Reactome: R-HSA-164939 Reactome: R-HSA-2219530 Reactome: R-HSA-389356 Reactome: R-HSA-389357 Reactome: R-HSA-389359 Reactome: R-HSA-6811558 |
Cellular Localisation | Membrane Single-Pass Type I Membrane Protein Isoform 3: Cell Surface |
Alternative Antibody Names | Anti-T-Cell-Specific Surface Glycoprotein Cd28 antibody Anti-Tp44 antibody Anti-Cd Antigen Cd28 antibody Anti-CD28 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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