产品详情
简单介绍:
Anti-CD226 antibody (19-336) (STJ115360)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-CD226 (19-336) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CD226 |
Gene ID: | 10666 |
Uniprot ID: | CD226_HUMAN |
Immunogen Region: | 19-336 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-336 of human CD226 (NP_006557.2). |
Immunogen Sequence: | EEVLWHTSVPFAENMSLECV YPSMGILTQVEWFKIGTQQD SIAIFSPTHGMVIRKPYAER VYFLNSTMASNNMTLFFRNA SEDDVGYYSCSLYTYPQGTW QKVIQVVQSDSFEAAVPSNS HIVSEPGKNVTLTCQPQMTW PVQAVRWEKIQPRQIDLLTY CNLVHGRNFTSKFPRQIVSN CSHGRWSVIVIPDVTVSDSG LYRCYLQASAGENETFVMRL TVAEGKTDNQYTLFVAGGT |
Tissue Specificity | Expressed by peripheral blood T-lymphocytes. |
Function | Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding. |
Protein Name | Cd226 Antigen Dnax Accessory Molecule 1 Dnam-1 Cd Antigen Cd226 |
Database Links | Reactome: R-HSA-198933 |
Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Cd226 Antigen antibody Anti-Dnax Accessory Molecule 1 antibody Anti-Dnam-1 antibody Anti-Cd Antigen Cd226 antibody Anti-CD226 antibody Anti-DNAM1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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