产品详情
简单介绍:
Human MMP11 (Stromelysin-3) CLIA Kit (STJC0000644)
详情介绍:
Applications: | CLIA |
Reactivity: | Human |
Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Sensitivity: | 18.75pg/mL |
Detection Limit: | 31.25~2000pg/mL |
Short Description: | This human MMP11 kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes. |
Storage Instruction: | If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual. |
Assay Time: | 3.5h |
Detection: | Chemiluminescence |
Gene Symbol: | MMP11 |
Gene ID: | 4320 |
Uniprot ID: | MMP11_HUMAN |
Specificity: | This kit recognizes Human MMP-11 in samples. No significant cross-reactivity or interference between Human MMP-11 and analogues was observed. |
Sample Type: | Serum, plasma and other biological fluids |
Tissue Specificity | Specifically expressed in stromal cells of breast carcinomas. |
Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
Function | May play an important role in the progression of epithelial malignancies. |
Protein Name | Stromelysin-3 Sl-3 St3 Matrix Metalloproteinase-11 Mmp-11 |
Database Links | Reactome: R-HSA-1442490 Reactome: R-HSA-1474228 Reactome: R-HSA-1592389 |
Cellular Localisation | Secreted Extracellular Space Extracellular Matrix |
Alternative CLIA Names | Stromelysin-3 CLIA kit Sl-3 CLIA kit St3 CLIA kit Matrix Metalloproteinase-11 CLIA kit Mmp-11 CLIA kit MMP11 CLIA kit STMY3 CLIA kit |
Specificity | This kit recognizes Human MMP-11 in samples. No significant cross-reactivity or interference between Human MMP-11 and analogues was observed. |
Reproducibility | Both intra-CV and inter-CV are |
Information sourced from Uniprot.org
Micro CLIA Plate (Dismountable) | 96T: 8 wells ×12 strips strips | -20℃, 6 months |
Reference Standard | 96T: 2 vials 48T: 1 vial | -20℃, 6 months |
Concentrated Biotinylated Detection Ab (100×) | 96T: 1 vial, 120 μL 60 μL | -20℃, 6 months |
Concentrated HRP Conjugate (100×) | 96T: 1 vial, 120 μL 60 μL | -20℃ (Protect from light), 6 months |
Reference Standard & Sample Diluent | 1 vial, 20 mL | 2-8°C, 6 months |
Biotinylated Detection Ab Diluent | 1 vial, 14 mL | 2-8°C, 6 months |
HRP Conjugate Diluent | 1 vial, 14 mL | 2-8°C, 6 months |
Concentrated Wash Buffer (25×) | 1 vial, 30 mL | 2-8°C, 6 months |
Substrate Reagent A | 1 vial, 5 mL | 2-8℃ (Protect from light) |
Substrate Reagent B | 1 vial, 5 mL | 2-8℃ (Protect from light) |
Plate Sealer | 5 pieces | |
Manual | 1 copy | |
Certificate of Analysis | 1 copy |
Serum(n=8) | 96-111 | 104 |
EDTA plasma(n=8) | 88-102 | 94 |
Cell culture media(n=8) | 100-113 | 107 |
Sample | 1.00 | 2.00 | 3.00 | 1.00 | 2.00 | 3.00 |
n | 20.00 | 20.00 | 20.00 | 20.00 | 20.00 | 20.00 |
Mean (pg/mL) | 110.56 | 282.34 | 841.22 | 116.47 | 301.58 | 826.08 |
Standard deviation | 12.25 | 32.84 | 82.27 | 9.67 | 35.19 | 65.34 |
CV (%) | 11.08 | 11.63 | 9.78 | 8.30 | 11.67 | 7.91 |
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