产品详情

  • 产品名称：Anti-BFSP1 antibody (281-540) (STJ22793)

  • 产品型号：STJ22793
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-BFSP1 antibody (281-540) (STJ22793)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-BFSP1 (281-540) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BFSP1
Gene ID: 631
Uniprot ID: BFSP1_HUMAN
Immunogen Region: 281-540
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 281-540 of human BFSP1 (NP_001155177.1).
Immunogen Sequence: EESESKFESESKEVSPLTQE GAPEDVPDGGQISKGFGKLY RKVKEKVRSPKEPETPTELY TKERHVLVTGDANYVDPRFY VSSITAKGGVAVSVAEDSVL YDGQVEPSPESPKPPLENGQ VGLQEKEDGQPIDQQPIDKE IEPDGAELEGPEEKREGEER DEESRRPCAMVTPGAEEPSI PEPPKPAADQDGAEVLGTRS RSLPEKGPPKALAYKTVEVV ESIEKISTESIQTYEETAV
Tissue Specificity Expressed in the cortex and nucleus of the retina lens (at protein level).
Post Translational Modifications Proteolytically cleaved during lens cell fiber differentiation with increased fragmentation as fiber cell age increases. Filensin C-terminal fragment: Myristoylated at Gly-434 following proteolytic cleavage at Asp-433. Filensin N-terminal fragment: Acetylated at Ala-42 following proteolytic cleavage at Leu-41.
Function Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA. Involved in altering the calcium regulation of MIP water permeability.
Protein Name Filensin
Beaded Filament Structural Protein 1
Lens Fiber Cell Beaded-Filament Structural Protein Cp 115
Cp115
Lens Intermediate Filament-Like Heavy
Lifl-H Cleaved Into - Filensin C-Terminal Fragment - Filensin N-Terminal Fragment
Cellular Localisation Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Cytoplasm
Cytoskeleton
Cell Cortex
Alternative Antibody Names Anti-Filensin antibody
Anti-Beaded Filament Structural Protein 1 antibody
Anti-Lens Fiber Cell Beaded-Filament Structural Protein Cp 115 antibody
Anti-Cp115 antibody
Anti-Lens Intermediate Filament-Like Heavy antibody
Anti-Lifl-H Cleaved Into - Filensin C-Terminal Fragment - Filensin N-Terminal Fragment antibody
Anti-BFSP1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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